Sabine Schumann
Head of Communications
EIT Health

Successes Listed

Next-level Alzheimer’s screening
Bringing mobile technologies to everyday practice
RAS-Q: The lung in a backpack
Treating cancer using anti-Myc peptides
Sustainable course: Advanced Management Programme on Health Innovation
Systematically improving chronic joint pain management across Europe
Removing bottlenecks that prevent use of Antibody Drug Conjugates
Non-invasive neural stimulator for movement disorders
Online course equips online learners to maximise healthcare data
Eliminating pneumothorax during lung biopsy
Innovating to solve global health challenges
Bringing intelligence to genetic data
An artificial pancreas for Type 1 diabetes patients
Self-management systems for respiratory diseases
Smart software for healthcare support
Innovative design-based methods in the workplace
Hundreds of citizens learn about health and active ageing, and provide essential feedback
Summer school using real-life cases to catalyse innovation finds new funders
A collaborative approach to innovation in diabetes care
Citizen-centred training for healthcare professionals
Improving the measurement of joint mobility
A more natural solution to chronic constipation
Clinical Innovation Fellowship spin-off seeks to improve medical tube success
Driving health innovation for the future
Empowering women entrepreneurs in health innovation
Smart-up Lab students and other present their ideas to investors
Improved prostate cancer diagnostics
State-of-the-art tool for dementia risk assessment
Device offers inexpensive alternative to surgery for common prostate problem
New platform allows everyone to link and mine life-changing data faster, smarter and simpler
Developing next-generation biological drugs for treating wounds in skin and mucosa
Non-medicinal soft robotic for the best night’s rest
A Star-Trek like medical device that provides the solution to killing multiresistant bacteria and treating chronic wounds

Success Stories

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Alzheimer's Disease Prediction Service

Alzheimer's Disease Prediction Service

Next-level Alzheimer’s screening

28 June 2018
Header Image
The Alzheimer's Disease Prediction Service (ADPS) is an EIT Health Innovation by Ideas project with the vision of making brain health measurable and thus actionable.

Current state-of-the-art diagnostic measures of Alzheimer's Disease are invasive (cerebrospinal fluid analysis), expensive (neuroimaging) and time-consuming (neuropsychological assessment) and thus have limited accessibility as frontline screening and diagnostic tools for AD. According to the 2014 Alzheimer report, only 35% of dementia cases are diagnosed early enough.

Innovation

After a 10-minute iPad-based test, ADPS is able to tell if someone will develop Alzheimer's Disease (AD) within six years, with an accuracy of 94%. ADPS will be one of the first validated solutions to enter the EU and US markets as a pre-symptomatic, computational biomarker to predict Alzheimer's risk for people over the age of 50.

Based on easily collectable digital behavioural markers, the platform measures cognitive outcomes using smartphone sensors. Neurologists are able to screen and monitor healthy, at-risk and Mild Cognitive Impairment/ AD Prodromal patients.

ADPS is currently deployed to neurologists and primary care physicians as a cognitive assessment tool for patients and it also distributed to global biopharmaceutical companies to assist with the discovery of novel treatments for AD.

Achievements so far:

  • longitudinal EU-funded studies at 22 sites with 4 500 candidates (2 700 AD prodromal);
  • 12 publications in major journals;
  • 240 independent publications supporting our methods;
  • initiated collaboration with Global Brain Health Institute -TILDA study;
  • endorsed by Alzheimer’s Europe and Alzheimer’s Association (USA);
  • Altoida, the spin-off responsible for ADPS, was recognized as a Rice Alliance 10 Most Promising Life Science Company at the 2017 Texas Life Science Forum in Houston, USA;
  • US FDA approval received;
  • working with NASA at the International Space Station on continuous brain monitoring of astronauts;
  • winner of EIT Innovators Award 2018.

Impact

The smartphone-based technology will simplify disease progression tracking and allow more precise and personalised prognosis, treatment and interventions for AD, one of society’s greatest challenges. More data will lead to better understanding of the disease and will be key to developing powerful new drugs and combining drugs with novel treatments.

Vision and goals

The project’s goal is to fight and ultimately solve one of the greatest challenges to society and the biggest burden to healthcare systems: Alzheimer’s Disease. Our smartphone-based technology will simplify disease progression tracking and allow more precise and personalised prognosis, treatment, and interventions for AD. More data will lead to better understanding of the disease and will be key to developing powerful new drugs and combining drugs with novel treatments.

Benefits of EIT Health support

The ADPS Innovation by Ideas project support enables the project to further evaluate the accuracy and performance of the ADPS prototype. At this stage in its development, the project also greatly benefits from the EIT Health network as it builds its reputation among key opinion leaders and enters the European market.

Team

  • Consorci Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
  • GMV Innovating Solutions
  • Trinity College Dublin
  • University of Barcelona

Contacts:

Innovation Project activity page

ioannis.tarnanas@gbhi.org

www.altoida.com

Download a Case Study of this Success Story.

Videos about ADPS: